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Acquired Fusion Activity of a Murine Coronavirus MHV-2 Variant with Mutations in the Proteolytic Cleavage Site and the Signal Sequence of the S Protein()

The spike (S) protein of a nonfusogenic murine coronavirus, MHV-2, was compared to the S protein of a variant with fusion activity, MHV-2f. Two amino acids differed between the S proteins of these viruses; one was located in the signal sequence and the other was in the putative cleavage site. The am...

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Detalles Bibliográficos
Autores principales: YAMADA, YASUKO K., TAKIMOTO, KAZUHIRO, YABE, MIKIKO, TAGUCHI, FUMIHIRO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131733/
https://www.ncbi.nlm.nih.gov/pubmed/9007076
http://dx.doi.org/10.1006/viro.1996.8313