Cargando…

Helicobacter pylori infection leads to KLF4 inactivation in gastric cancer through a TET1‐mediated DNA methylation mechanism

Krüppel‐like factor 4 (KLF4) has a tumor suppressor role in the progression of gastric cancer (GC), and inhibition or loss of KLF4 expression was identified in GC. The aim of this study was to explore the new molecular mechanism of KLF4 inactivation in gastric cancer. Herein, we report that Helicoba...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Rongrong, Liu, Zhengxia, Xu, Wenting, Song, Le, Ren, Haifeng, Ou, Yang, Liu, Yakun, Wang, Siying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131848/
https://www.ncbi.nlm.nih.gov/pubmed/32017451
http://dx.doi.org/10.1002/cam4.2892