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Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124‐2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions

The decision to treat a cervical squamous intraepithelial lesion (SIL) by loop electrosurgical excision procedure (LEEP) relies heavily on a colposcopy‐directed biopsy showing high‐grade (H)SIL. Diagnosis is often supported by p16, an immunohistochemical (IHC) biomarker of high‐risk (hr)HPV E7 gene...

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Detalles Bibliográficos
Autores principales: Leeman, Annemiek, Jenkins, David, del Pino, Marta, Ordi, Jaume, Torné, Aureli, Doorbar, John, Meijer, Chris J. L. M., van Kemenade, Folkert J., Quint, Wim G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131853/
https://www.ncbi.nlm.nih.gov/pubmed/32022461
http://dx.doi.org/10.1002/cam4.2855