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Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124‐2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions
The decision to treat a cervical squamous intraepithelial lesion (SIL) by loop electrosurgical excision procedure (LEEP) relies heavily on a colposcopy‐directed biopsy showing high‐grade (H)SIL. Diagnosis is often supported by p16, an immunohistochemical (IHC) biomarker of high‐risk (hr)HPV E7 gene...
Autores principales: | Leeman, Annemiek, Jenkins, David, del Pino, Marta, Ordi, Jaume, Torné, Aureli, Doorbar, John, Meijer, Chris J. L. M., van Kemenade, Folkert J., Quint, Wim G. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131853/ https://www.ncbi.nlm.nih.gov/pubmed/32022461 http://dx.doi.org/10.1002/cam4.2855 |
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