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FoxO1 regulates TLR4/MyD88/MD2‐NF‐κB inflammatory signalling in mucosal barrier injury of inflammatory bowel disease

In this study, FoxO1 transgenic mice (transgenic, FoxO1‐Tg) and C57BL/6 wild‐type (wild‐type, FoxO1‐WT) mice were used to establish chronic colitis by drinking water containing dextran sulphate sodium (DSS). Afterwards, we observed the life changes in mice and assessed the pathological changes by H&...

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Detalles Bibliográficos
Autores principales: Han, Chenyang, Guo, Li, Sheng, Yongjia, Yang, Yi, Wang, Jin, Gu, Yanling, Li, Wenyan, Zhou, Xiaohong, Jiao, Qingcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131908/
https://www.ncbi.nlm.nih.gov/pubmed/32057181
http://dx.doi.org/10.1111/jcmm.15075