Lobetyolin induces apoptosis of colon cancer cells by inhibiting glutamine metabolism

The purpose of the present study was to evaluate the anti‐cancer property of Lobetyolin on colorectal cancer and explore its potential mechanism. Lobetyolin was incubated with HCT‐116 cells in the absence or presence of ASCT2 inhibitor Benser or p53 inhibitor Pifithrin‐α. The levels of glutamine, gl...

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Detalles Bibliográficos
Autores principales: He, Wei, Tao, Weiwei, Zhang, Feng, Jie, Qian, He, Yun, Zhu, Wei, Tan, Jiani, Shen, Weixing, Li, Liu, Yang, Ye, Cheng, Haibo, Sun, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131919/
https://www.ncbi.nlm.nih.gov/pubmed/31990147
http://dx.doi.org/10.1111/jcmm.15009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131919/
https://www.ncbi.nlm.nih.gov/pubmed/31990147
http://dx.doi.org/10.1111/jcmm.15009

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