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AQP1 suppression by ATF4 triggers trabecular meshwork tissue remodelling in ET‐1‐induced POAG

Primary open‐angle glaucoma (POAG) is the second leading cause of irreversible blindness worldwide. Increased endothelin‐1 (ET‐1) has been observed in aqueous humour (AH) of POAG patients, resulting in an increase in the out‐flow resistance of the AH. However, the underlining mechanisms remain elusi...

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Detalles Bibliográficos
Autores principales: Zhao, Yingying, Zhu, Huazhang, Yang, Yangfan, Ye, Yiming, Yao, Youli, Huang, Xiaoyan, Zhang, Yixiang, Shu, Xingsheng, Chen, Xianxiong, Yang, Yatao, Ma, Junxian, Cheng, Le, Wang, Xiaomei, Ying, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131939/
https://www.ncbi.nlm.nih.gov/pubmed/32052937
http://dx.doi.org/10.1111/jcmm.15032