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AQP1 suppression by ATF4 triggers trabecular meshwork tissue remodelling in ET‐1‐induced POAG
Primary open‐angle glaucoma (POAG) is the second leading cause of irreversible blindness worldwide. Increased endothelin‐1 (ET‐1) has been observed in aqueous humour (AH) of POAG patients, resulting in an increase in the out‐flow resistance of the AH. However, the underlining mechanisms remain elusi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131939/ https://www.ncbi.nlm.nih.gov/pubmed/32052937 http://dx.doi.org/10.1111/jcmm.15032 |