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Dracorhodin perchlorate inhibits osteoclastogenesis through repressing RANKL‐stimulated NFATc1 activity

Osteolytic skeletal disorders are caused by an imbalance in the osteoclast and osteoblast function. Suppressing the differentiation and resorptive function of osteoclast is a key strategy for treating osteolytic diseases. Dracorhodin perchlorate (D.P), an active component from dragon blood resin, ha...

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Detalles Bibliográficos
Autores principales: Liu, Yuhao, Wang, Ziyi, Ma, Chao, Wei, Zhenquan, Chen, Kai, Wang, Chao, Zhou, Chi, Chen, Leilei, Zhang, Qingwen, Chen, Zhenqiu, He, Wei, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131942/
https://www.ncbi.nlm.nih.gov/pubmed/31965715
http://dx.doi.org/10.1111/jcmm.15003