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Methyltransferase like 3 promotes colorectal cancer proliferation by stabilizing CCNE1 mRNA in an m6A‐dependent manner

m6A modification is the most prevalent RNA modification in eukaryotes. As the critical N6‐methyladenosine (m6A) methyltransferase, the roles of methyltransferase like 3 (METTL3) in colorectal cancer (CRC) are controversial. Here, we confirmed that METTL3, a critical m6A methyltransferase, could faci...

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Detalles Bibliográficos
Autores principales: Zhu, Wei, Si, Yan, Xu, Jun, Lin, Yu, Wang, Jing‐Zi, Cao, Mengda, Sun, Shanwen, Ding, Qiang, Zhu, Lingjun, Wei, Ji‐Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131945/
https://www.ncbi.nlm.nih.gov/pubmed/32039568
http://dx.doi.org/10.1111/jcmm.15042