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Mechanism of indoleamine 2, 3‐dioxygenase inhibiting cardiac allograft rejection in mice

Indoleamine 2, 3‐dioxygenase (IDO)‐mediated regulation of tryptophan metabolism plays an important role in immune tolerance in transplantation, but it has not been elucidated which mechanism specifically induces the occurrence of immune tolerance. Our study revealed that IDO exerts immunosuppressive...

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Detalles Bibliográficos
Autores principales: Li, Chuan, Sun, Zhaonan, Yuan, Fang, Zhao, Zhicheng, Zhang, Jiehong, Zhang, Baotong, Li, Hongyue, Liu, Tong, Dai, Xiangchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131949/
https://www.ncbi.nlm.nih.gov/pubmed/32027774
http://dx.doi.org/10.1111/jcmm.15024