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Mechanism of indoleamine 2, 3‐dioxygenase inhibiting cardiac allograft rejection in mice
Indoleamine 2, 3‐dioxygenase (IDO)‐mediated regulation of tryptophan metabolism plays an important role in immune tolerance in transplantation, but it has not been elucidated which mechanism specifically induces the occurrence of immune tolerance. Our study revealed that IDO exerts immunosuppressive...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131949/ https://www.ncbi.nlm.nih.gov/pubmed/32027774 http://dx.doi.org/10.1111/jcmm.15024 |