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Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

INTRODUCTION: Disruption of metabolic function is a recognized feature of late onset Alzheimer's disease (LOAD). We sought to determine whether similar metabolic pathways are implicated in adults with Down syndrome (DS) who have increased risk for Alzheimer's disease (AD). METHODS: We exam...

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Detalles Bibliográficos
Autores principales: Mapstone, Mark, Gross, Thomas J, Macciardi, Fabio, Cheema, Amrita K, Petersen, Melissa, Head, Elizabeth, Handen, Benjamin L, Klunk, William E, Christian, Bradley T, Silverman, Wayne, Lott, Ira T, Schupf, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131985/
https://www.ncbi.nlm.nih.gov/pubmed/32258359
http://dx.doi.org/10.1002/dad2.12028