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Specialized cytonemes induce self-organization of stem cells

Spatial cellular organization is fundamental for embryogenesis. Remarkably, coculturing embryonic stem cells (ESCs) and trophoblast stem cells (TSCs) recapitulates this process, forming embryo-like structures. However, mechanisms driving ESC–TSC interaction remain elusive. We describe specialized ES...

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Detalles Bibliográficos
Autores principales: Junyent, Sergi, Garcin, Clare L., Szczerkowski, James L. A., Trieu, Tung-Jui, Reeves, Joshua, Habib, Shukry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132109/
https://www.ncbi.nlm.nih.gov/pubmed/32184326
http://dx.doi.org/10.1073/pnas.1920837117