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Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation
BACKGROUND: Hypertrophic scar (HS) is characterized by the increased proliferation and decreased apoptosis of myofibroblasts. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts. Thus, the stimulation of myofibroblast apoptosis is a possible treatment for HS....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132150/ https://www.ncbi.nlm.nih.gov/pubmed/32251998 http://dx.doi.org/10.1016/j.ebiom.2020.102715 |