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Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation

BACKGROUND: Hypertrophic scar (HS) is characterized by the increased proliferation and decreased apoptosis of myofibroblasts. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts. Thus, the stimulation of myofibroblast apoptosis is a possible treatment for HS....

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Detalles Bibliográficos
Autores principales: Feng, Yi, Wu, Jun-Jie, Sun, Zi-Li, Liu, Si-Yu, Zou, Ming-Li, Yuan, Zheng-Dong, Yu, Shun, Lv, Guo-Zhong, Yuan, Feng-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132150/
https://www.ncbi.nlm.nih.gov/pubmed/32251998
http://dx.doi.org/10.1016/j.ebiom.2020.102715