Cargando…
Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation
BACKGROUND: Hypertrophic scar (HS) is characterized by the increased proliferation and decreased apoptosis of myofibroblasts. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts. Thus, the stimulation of myofibroblast apoptosis is a possible treatment for HS....
Autores principales: | Feng, Yi, Wu, Jun-Jie, Sun, Zi-Li, Liu, Si-Yu, Zou, Ming-Li, Yuan, Zheng-Dong, Yu, Shun, Lv, Guo-Zhong, Yuan, Feng-Lai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132150/ https://www.ncbi.nlm.nih.gov/pubmed/32251998 http://dx.doi.org/10.1016/j.ebiom.2020.102715 |
Ejemplares similares
-
Direct and Indirect Roles of Macrophages in Hypertrophic Scar Formation
por: Feng, Yi, et al.
Publicado: (2019) -
Emerging Role of IL-10 in Hypertrophic Scars
por: Sun, Zi-Li, et al.
Publicado: (2020) -
ABT-263 Reduces Hypertrophic Scars by Targeting Apoptosis of Myofibroblasts
por: Yang, Xiaolan, et al.
Publicado: (2021) -
Effect of Keratinocytes on Myofibroblasts in Hypertrophic Scars
por: Hun Choi, Dong, et al.
Publicado: (2019) -
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis
por: Dong, Yunxian, et al.
Publicado: (2022)