Two Catalytic Annulation Modes via Cu-Allenylidenes with Sulfur Ylides that Are Dominated by the Presence or Absence of Trifluoromethyl Substituents

We disclose the Cu-catalyzed enantioselective synthesis of 3-methyl-3-propargyl-indolines, which contain a quaternary stereogenic carbon center, via the decarboxylative [4 + 1] annulation of 4-methyl-4-propargyl-benzoxazinanones with variety of sulfur ylides. The reaction proceeds predominantly thro...

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Detalles Bibliográficos
Autores principales: Gannarapu, Malla Reddy, Zhou, Jun, Jiang, Bingyao, Shibata, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132161/
https://www.ncbi.nlm.nih.gov/pubmed/32259670
http://dx.doi.org/10.1016/j.isci.2020.100994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132161/
https://www.ncbi.nlm.nih.gov/pubmed/32259670
http://dx.doi.org/10.1016/j.isci.2020.100994

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