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Evolution of the immune landscape during progression of pancreatic intraductal papillary mucinous neoplasms to invasive cancer

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer, which is characterized by an immunosuppressive microenvironment. Yet, the spatial distribution of the immune infiltrate and how it changes during IPMN progression is just beginning to be understo...

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Detalles Bibliográficos
Autores principales: Roth, Susanne, Zamzow, Katharina, Gaida, Matthias M., Heikenwälder, Mathias, Tjaden, Christine, Hinz, Ulf, Bose, Promita, Michalski, Christoph W., Hackert, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132171/
https://www.ncbi.nlm.nih.gov/pubmed/32259711
http://dx.doi.org/10.1016/j.ebiom.2020.102714