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Adherens junction remodelling during mitotic rounding of pseudostratified epithelial cells

Epithelial cells undergo cortical rounding at the onset of mitosis to enable spindle orientation in the plane of the epithelium. In cuboidal epithelia in culture, the adherens junction protein E‐cadherin recruits Pins/LGN/GPSM2 and Mud/NuMA to orient the mitotic spindle. In the pseudostratified colu...

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Detalles Bibliográficos
Autores principales: Aguilar‐Aragon, Mario, Bonello, Teresa T, Bell, Graham P, Fletcher, Georgina C, Thompson, Barry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132200/
https://www.ncbi.nlm.nih.gov/pubmed/32030856
http://dx.doi.org/10.15252/embr.201949700