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Interleukin-35 sensitizes monocytes from patients with asthma to glucocorticoid therapy by regulating p38 MAPK

The activation of monocytes and macrophages is associated with steroid-resistant (SR) asthma. Interleukin-35 (IL-35) is an important anti-inflammatory cytokine, but its regulatory effects on monocytes in patients with SR asthma is not fully understood. Based on clinical response to oral prednisolone...

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Detalles Bibliográficos
Autores principales: Qian, Lei, Xu, Donghui, Xue, Fangsu, Li, Ming, Wang, Xushan, Liu, Guangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132241/
https://www.ncbi.nlm.nih.gov/pubmed/32266020
http://dx.doi.org/10.3892/etm.2020.8586