Cargando…
Interleukin-35 sensitizes monocytes from patients with asthma to glucocorticoid therapy by regulating p38 MAPK
The activation of monocytes and macrophages is associated with steroid-resistant (SR) asthma. Interleukin-35 (IL-35) is an important anti-inflammatory cytokine, but its regulatory effects on monocytes in patients with SR asthma is not fully understood. Based on clinical response to oral prednisolone...
Autores principales: | Qian, Lei, Xu, Donghui, Xue, Fangsu, Li, Ming, Wang, Xushan, Liu, Guangliang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132241/ https://www.ncbi.nlm.nih.gov/pubmed/32266020 http://dx.doi.org/10.3892/etm.2020.8586 |
Ejemplares similares
-
P38 MAPK and glucocorticoid receptor crosstalk in bronchial epithelial cells
por: Lea, Simon, et al.
Publicado: (2020) -
Impact of ozone exposure on the response to glucocorticoid in a mouse model of asthma: involvements of p38 MAPK and MKP-1
por: Bao, Aihua, et al.
Publicado: (2014) -
Activated p38 MAPK in Peripheral Blood Monocytes of Steroid Resistant Asthmatics
por: Li, Ling-bo, et al.
Publicado: (2015) -
Interleukin-1β regulates the expression of glucocorticoid receptor isoforms in nasal polyps in vitro via p38 MAPK and JNK signal transduction pathways
por: Wang, Zhenlin, et al.
Publicado: (2015) -
Interleukin-35 exhibits protective effects in a rat model of hypoxic-ischemic encephalopathy through the inhibition of microglia-mediated inflammation
por: Liu, Guangliang, et al.
Publicado: (2022)