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Diterpene Ginkgolides Exert an Antidepressant Effect Through the NT3-TrkA and Ras-MAPK Pathways

BACKGROUND: Depression is a highly prevalent mental illness that severely impacts the quality of life of affected individuals. Our recent studies demonstrated that diterpene ginkgolides (DG) have antidepressant effects in mice. However, the underlying molecular mechanisms remained much unclear. METH...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Bai, Shunjie, Wang, Wei, Chen, Zhi, Chen, Jianjun, Liang, Zihong, Qi, Xunzhong, Shen, Hailan, Xie, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132272/
https://www.ncbi.nlm.nih.gov/pubmed/32308365
http://dx.doi.org/10.2147/DDDT.S229145