c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria

Antibiotic-producing Streptomyces use the diadenylate cyclase DisA to synthesize the nucleotide second messenger c-di-AMP, but the mechanism for terminating c-di-AMP signaling and the proteins that bind the molecule to effect signal transduction are unknown. Here, we identify the AtaC protein as a c...

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Detalles Bibliográficos
Autores principales: Latoscha, Andreas, Drexler, David Jan, Al-Bassam, Mahmoud M., Bandera, Adrian M., Kaever, Volkhard, Findlay, Kim C., Witte, Gregor, Tschowri, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132281/
https://www.ncbi.nlm.nih.gov/pubmed/32188788
http://dx.doi.org/10.1073/pnas.1917080117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132281/
https://www.ncbi.nlm.nih.gov/pubmed/32188788
http://dx.doi.org/10.1073/pnas.1917080117

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