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c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria
Antibiotic-producing Streptomyces use the diadenylate cyclase DisA to synthesize the nucleotide second messenger c-di-AMP, but the mechanism for terminating c-di-AMP signaling and the proteins that bind the molecule to effect signal transduction are unknown. Here, we identify the AtaC protein as a c...
Autores principales: | Latoscha, Andreas, Drexler, David Jan, Al-Bassam, Mahmoud M., Bandera, Adrian M., Kaever, Volkhard, Findlay, Kim C., Witte, Gregor, Tschowri, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132281/ https://www.ncbi.nlm.nih.gov/pubmed/32188788 http://dx.doi.org/10.1073/pnas.1917080117 |
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