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Rbm24 controls poly(A) tail length and translation efficiency of crystallin mRNAs in the lens via cytoplasmic polyadenylation

Lens transparency is established by abundant accumulation of crystallin proteins and loss of organelles in the fiber cells. It requires an efficient translation of lens messenger RNAs (mRNAs) to overcome the progressively reduced transcriptional activity that results from denucleation. Inappropriate...

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Detalles Bibliográficos
Autores principales: Shao, Ming, Lu, Tong, Zhang, Chong, Zhang, Yi-Zhuang, Kong, Shu-Hui, Shi, De-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132282/
https://www.ncbi.nlm.nih.gov/pubmed/32170011
http://dx.doi.org/10.1073/pnas.1917922117