MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF‐β1 levels

Mutations in the CD18 gene encoding the common β‐chain of β2 integrins result in impaired wound healing in humans and mice suffering from leukocyte adhesion deficiency syndrome type 1 (LAD1). Transplantation of adipose tissue‐derived mesenchymal stem cells (MSCs) restores normal healing of CD18(−/−)...

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Detalles Bibliográficos
Autores principales: Jiang, Dongsheng, Singh, Karmveer, Muschhammer, Jana, Schatz, Susanne, Sindrilaru, Anca, Makrantonaki, Evgenia, Qi, Yu, Wlaschek, Meinhard, Scharffetter‐Kochanek, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132342/
https://www.ncbi.nlm.nih.gov/pubmed/32080965
http://dx.doi.org/10.15252/embr.201949115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132342/
https://www.ncbi.nlm.nih.gov/pubmed/32080965
http://dx.doi.org/10.15252/embr.201949115

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