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MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF‐β1 levels
Mutations in the CD18 gene encoding the common β‐chain of β2 integrins result in impaired wound healing in humans and mice suffering from leukocyte adhesion deficiency syndrome type 1 (LAD1). Transplantation of adipose tissue‐derived mesenchymal stem cells (MSCs) restores normal healing of CD18(−/−)...
Autores principales: | Jiang, Dongsheng, Singh, Karmveer, Muschhammer, Jana, Schatz, Susanne, Sindrilaru, Anca, Makrantonaki, Evgenia, Qi, Yu, Wlaschek, Meinhard, Scharffetter‐Kochanek, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132342/ https://www.ncbi.nlm.nih.gov/pubmed/32080965 http://dx.doi.org/10.15252/embr.201949115 |
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