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Using protein engineering to understand and modulate aggregation
Protein aggregation occurs through a variety of mechanisms, initiated by the unfolded, non-native, or even the native state itself. Understanding the molecular mechanisms of protein aggregation is challenging, given the array of competing interactions that control solubility, stability, cooperativit...
Autores principales: | Ebo, Jessica S, Guthertz, Nicolas, Radford, Sheena E, Brockwell, David J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132541/ https://www.ncbi.nlm.nih.gov/pubmed/32087409 http://dx.doi.org/10.1016/j.sbi.2020.01.005 |
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