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A robust test for X-chromosome genetic association accounting for X-chromosome inactivation and imprinting

The X chromosome is known to play an important role in many sex-specific diseases. However, only a few single-nucleotide polymorphisms on the X chromosome have been found to be associated with diseases. Compared to the autosomes, conducting association tests on the X chromosome is more intractable d...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Xu, Si-Qi, Liu, Wei, Fung, Wing Kam, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132553/
https://www.ncbi.nlm.nih.gov/pubmed/32234109
http://dx.doi.org/10.1017/S0016672320000026