UPLC–MS/MS assay for quantification of an inhibitor of kinases (Foretinib) in plasma: Application to a pharmacokinetic study in rats

Foretinib, an oral multikinase inhibitor, is known to have anti-tumor effects against cancers. The doses and the levels of foretinib vary based on the type of cancer to be treated. An accurate and precise method is required to determine the level of foretinib and its pharmacokinetics. Here, we devel...

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Detalles Bibliográficos
Autores principales: Ezzeldin, Essam, Iqbal, Muzaffar, Asiri, Yousif A., Ali, Azza A., El Nahhas, Toqa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132596/
https://www.ncbi.nlm.nih.gov/pubmed/32273795
http://dx.doi.org/10.1016/j.jsps.2020.01.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132596/
https://www.ncbi.nlm.nih.gov/pubmed/32273795
http://dx.doi.org/10.1016/j.jsps.2020.01.013

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