Design and encapsulation of anticancer dual HSP27 and HER2 inhibitor into low density lipoprotein to target ovarian cancer cells

Tumor cells overexpress low-density lipoprotein (LDL) receptors (LDL-r). Hence, LDL is proposed as a targeting shuttle of anticancer drugs. Therefore, the objective of this study was to synthesize a dual inhibitor of heat shock protein 27 (HSP27) and human epidermal growth factor receptor 2 (HER2) c...

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Detalles Bibliográficos
Autores principales: Alhadad, Laila J., Harisa, Gamaleldin I., Alanazi, Fars K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132616/
https://www.ncbi.nlm.nih.gov/pubmed/32273796
http://dx.doi.org/10.1016/j.jsps.2020.01.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132616/
https://www.ncbi.nlm.nih.gov/pubmed/32273796
http://dx.doi.org/10.1016/j.jsps.2020.01.020

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