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A topological analysis of difference topology experiments of condensin with topoisomerase II

An experimental technique called difference topology combined with the mathematics of tangle analysis has been used to unveil the structure of DNA bound by the Mu transpososome. However, difference topology experiments can be difficult and time consuming. We discuss a modification that greatly simpl...

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Detalles Bibliográficos
Autores principales: Kim, Soojeong, Darcy, Isabel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132813/
https://www.ncbi.nlm.nih.gov/pubmed/32184229
http://dx.doi.org/10.1242/bio.048603