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Prevalence of the co-prescription of tamoxifen and CYP2D6 inhibitors in Saudi population: A cross sectional study

Consumption of Cytochrome P450 2D6 (CYP2D6) inhibiting drugs along with tamoxifen treatment results in decrease in plasma concentration of endoxifen, the major active tamoxifen metabolite. Simultaneous use of CYP2D6 inhibitors, such as selective serotonin reuptake inhibitors (SSIs), as well as lesse...

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Detalles Bibliográficos
Autores principales: Arafah, Azher, Yakout, Khalid, Rehman, Muneeb U., Mohammed Alsharif, Ammar, AlJawadi, Mohammad H., Al-Omar, Hussain Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132831/
https://www.ncbi.nlm.nih.gov/pubmed/32273802
http://dx.doi.org/10.1016/j.jsps.2020.02.004