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HIF1α overexpression enhances diabetic wound closure in high glucose and low oxygen conditions by promoting adipose-derived stem cell paracrine function and survival

BACKGROUND: Adipose-derived stem cell (ADSC) transplantation is a promising strategy to promote wound healing because of the paracrine function of stem cells. However, glucose-associated effects on stem cell paracrine function and survival contribute to impaired wound closure in patients with diabet...

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Detalles Bibliográficos
Autores principales: Xu, Jin, Liu, Xiaoyu, Zhao, Feng, Zhang, Ying, Wang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132964/
https://www.ncbi.nlm.nih.gov/pubmed/32248837
http://dx.doi.org/10.1186/s13287-020-01654-2