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HIF1α overexpression enhances diabetic wound closure in high glucose and low oxygen conditions by promoting adipose-derived stem cell paracrine function and survival
BACKGROUND: Adipose-derived stem cell (ADSC) transplantation is a promising strategy to promote wound healing because of the paracrine function of stem cells. However, glucose-associated effects on stem cell paracrine function and survival contribute to impaired wound closure in patients with diabet...
Autores principales: | Xu, Jin, Liu, Xiaoyu, Zhao, Feng, Zhang, Ying, Wang, Zhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132964/ https://www.ncbi.nlm.nih.gov/pubmed/32248837 http://dx.doi.org/10.1186/s13287-020-01654-2 |
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