Assessing graph-based read mappers against a baseline approach highlights strengths and weaknesses of current methods

BACKGROUND: Graph-based reference genomes have become popular as they allow read mapping and follow-up analyses in settings where the exact haplotypes underlying a high-throughput sequencing experiment are not precisely known. Two recent papers show that mapping to graph-based reference genomes can...

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Detalles Bibliográficos
Autores principales: Grytten, Ivar, Rand, Knut D., Nederbragt, Alexander J., Sandve, Geir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132971/
https://www.ncbi.nlm.nih.gov/pubmed/32252628
http://dx.doi.org/10.1186/s12864-020-6685-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132971/
https://www.ncbi.nlm.nih.gov/pubmed/32252628
http://dx.doi.org/10.1186/s12864-020-6685-y

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