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Assessing graph-based read mappers against a baseline approach highlights strengths and weaknesses of current methods
BACKGROUND: Graph-based reference genomes have become popular as they allow read mapping and follow-up analyses in settings where the exact haplotypes underlying a high-throughput sequencing experiment are not precisely known. Two recent papers show that mapping to graph-based reference genomes can...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132971/ https://www.ncbi.nlm.nih.gov/pubmed/32252628 http://dx.doi.org/10.1186/s12864-020-6685-y |