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The impact of hyperpolarization-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium KCNQ/Kv7 channels on primary microglia function

BACKGROUND: Microglia are essential to maintain cell homeostasis in the healthy brain and are activated after brain injury. Upon activation, microglia polarize towards different phenotypes. The course of microglia activation is complex and depends on signals in the surrounding milieu. Recently, it h...

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Detalles Bibliográficos
Autores principales: Vay, Sabine Ulrike, Flitsch, Lea Jessica, Rabenstein, Monika, Monière, Helena, Jakovcevski, Igor, Andjus, Pavle, Bijelic, Dunja, Blaschke, Stefan, Walter, Helene Luise, Fink, Gereon Rudolf, Schroeter, Michael, Rueger, Maria Adele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132998/
https://www.ncbi.nlm.nih.gov/pubmed/32248813
http://dx.doi.org/10.1186/s12974-020-01779-4