Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose

BACKGROUND: Despite the emergence of cell-free DNA (cfDNA) as a clinical biomarker in cancer, the tissue origins of cfDNA in healthy individuals have to date been inferred only by indirect and relative measurement methods, such as tissue-specific methylation and nucleosomal profiling. METHODS: We pe...

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Detalles Bibliográficos
Autores principales: Laurent, Danny, Semple, Fiona, Starkey Lewis, Philip J., Rose, Elaine, Black, Holly A., Coe, Jennifer, Forbes, Stuart J., Arends, Mark J., Dear, James W., Aitman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133021/
https://www.ncbi.nlm.nih.gov/pubmed/32252771
http://dx.doi.org/10.1186/s12920-020-0705-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133021/
https://www.ncbi.nlm.nih.gov/pubmed/32252771
http://dx.doi.org/10.1186/s12920-020-0705-2

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