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The Secret Life of ACE2 as a Receptor for the SARS Virus

The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion.

Detalles Bibliográficos
Autor principal: Dimitrov, Dimiter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press. 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133233/
https://www.ncbi.nlm.nih.gov/pubmed/14675530
http://dx.doi.org/10.1016/S0092-8674(03)00976-0