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The Secret Life of ACE2 as a Receptor for the SARS Virus
The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press.
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133233/ https://www.ncbi.nlm.nih.gov/pubmed/14675530 http://dx.doi.org/10.1016/S0092-8674(03)00976-0 |
| Sumario: | The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion. |
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