Cargando…
The Secret Life of ACE2 as a Receptor for the SARS Virus
The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion.
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press.
2003
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133233/ https://www.ncbi.nlm.nih.gov/pubmed/14675530 http://dx.doi.org/10.1016/S0092-8674(03)00976-0 |
| _version_ | 1783517586847170560 |
|---|---|
| author | Dimitrov, Dimiter S |
| author_facet | Dimitrov, Dimiter S |
| author_sort | Dimitrov, Dimiter S |
| collection | PubMed |
| description | The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion. |
| format | Online Article Text |
| id | pubmed-7133233 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2003 |
| publisher | Cell Press. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-71332332020-04-08 The Secret Life of ACE2 as a Receptor for the SARS Virus Dimitrov, Dimiter S Cell Preview The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion. Cell Press. 2003-12-12 2003-12-16 /pmc/articles/PMC7133233/ /pubmed/14675530 http://dx.doi.org/10.1016/S0092-8674(03)00976-0 Text en Copyright © 2003 Cell Press. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Preview Dimitrov, Dimiter S The Secret Life of ACE2 as a Receptor for the SARS Virus |
| title | The Secret Life of ACE2 as a Receptor for the SARS Virus |
| title_full | The Secret Life of ACE2 as a Receptor for the SARS Virus |
| title_fullStr | The Secret Life of ACE2 as a Receptor for the SARS Virus |
| title_full_unstemmed | The Secret Life of ACE2 as a Receptor for the SARS Virus |
| title_short | The Secret Life of ACE2 as a Receptor for the SARS Virus |
| title_sort | secret life of ace2 as a receptor for the sars virus |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133233/ https://www.ncbi.nlm.nih.gov/pubmed/14675530 http://dx.doi.org/10.1016/S0092-8674(03)00976-0 |
| work_keys_str_mv | AT dimitrovdimiters thesecretlifeoface2asareceptorforthesarsvirus AT dimitrovdimiters secretlifeoface2asareceptorforthesarsvirus |