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Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

Structural similarity between viral T cell epitopes and self-peptides could lead to the induction of an autoaggressive T cell response. Based on the structural requirements for both MHC class 11 binding and TCR recognition of an immunodominant myelin basic protein (MBP) peptide, criteria for a data...

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Detalles Bibliográficos
Autores principales: Wucherpfennig, Kai W, Strominger, Jack L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133435/
https://www.ncbi.nlm.nih.gov/pubmed/7534214
http://dx.doi.org/10.1016/0092-8674(95)90348-8