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Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

We have produced transgenic mouse strains harboring class II major histocompatibility complex or interferon-gamma genes linked to the human insulin promoter. These experiments were designed to investigate the consequences of the expression of immunological effector molecules by nonimmunological cell...

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Detalles Bibliográficos
Autores principales: Sarvetnick, Nora, Liggitt, Denny, Pitts, Sharon L., Hansen, Stanley E., Stewart, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133464/
https://www.ncbi.nlm.nih.gov/pubmed/2449974
http://dx.doi.org/10.1016/0092-8674(88)90414-X