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Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma
We have produced transgenic mouse strains harboring class II major histocompatibility complex or interferon-gamma genes linked to the human insulin promoter. These experiments were designed to investigate the consequences of the expression of immunological effector molecules by nonimmunological cell...
Autores principales: | Sarvetnick, Nora, Liggitt, Denny, Pitts, Sharon L., Hansen, Stanley E., Stewart, Timothy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133464/ https://www.ncbi.nlm.nih.gov/pubmed/2449974 http://dx.doi.org/10.1016/0092-8674(88)90414-X |
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