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The Group-Specific Murine Coronavirus Genes Are Not Essential, but Their Deletion, by Reverse Genetics, Is Attenuating in the Natural Host

In addition to a characteristic set of essential genes coronaviruses contain several so-called group-specific genes. These genes differ distinctly among the three coronavirus groups and are specific for each group. While the essential genes encode replication and structural functions, hardly anythin...

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Detalles Bibliográficos
Autores principales: de Haan, Cornelis A.M., Masters, Paul S., Shen, Xiaolan, Weiss, Susan, Rottier, Peter J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science (USA). 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133727/
https://www.ncbi.nlm.nih.gov/pubmed/12036329
http://dx.doi.org/10.1006/viro.2002.1412