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The diagnostic challenges and clinical course of a myeloid/lymphoid neoplasm with eosinophilia and ZBTB20-JAK2 gene fusion presenting as B-lymphoblastic leukemia

We report the diagnostic challenges and the clinical course of a patient with an extraordinary presentation of B-lymphoblastic leukemia (B-ALL) with eosinophilia. We identified a novel ZBTB20-JAK2 gene fusion as a chimeric RNA transcript using the Archer platform. This gene fusion from the same pati...

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Detalles Bibliográficos
Autores principales: Lee, Winston Y., Pfau, Ruthann B., Choi, Sarah M., Yang, Jiong, Xiao, Hong, Putnam, Eileen M., Ryan, Russell JH., Bixby, Dale L., Shao, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133749/
https://www.ncbi.nlm.nih.gov/pubmed/32238402
http://dx.doi.org/10.1101/mcs.a004937