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High water vs. ad libitum water intake for autosomal dominant polycystic kidney disease: a randomized controlled feasibility trial

BACKGROUND: Vasopressin stimulates cyst growth in autosomal dominant polycystic kidney disease (ADPKD) and is a key therapeutic target. Evaluation of high water intake as an alternative to pharmacological vasopressin blockade is supported by patients. However feasibility, safety and adherence-promot...

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Detalles Bibliográficos
Autores principales: El-Damanawi, R, Lee, M, Harris, T, Cowley, L B, Bond, S, Pavey, H, Sandford, R N, Wilkinson, I B, Karet Frankl, F E, Hiemstra, T F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133783/
https://www.ncbi.nlm.nih.gov/pubmed/31665476
http://dx.doi.org/10.1093/qjmed/hcz278