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Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis

Modification of the genetic content of cultured cells or of whole animals is now a key strategy in both basic biological research and applied biotechnology. Yet obtaining the desired level and specificity of expression of an introduced gene remains highly problematic. One solution could be to couple...

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Detalles Bibliográficos
Autores principales: Mountford, Peter S., Smith, Austin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133804/
https://www.ncbi.nlm.nih.gov/pubmed/7540337
http://dx.doi.org/10.1016/S0168-9525(00)89040-X