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Prophylactic and therapeutic activities of 7-thia-8-oxoguanosine against Punta Toro virus infections in mice

The biological response modifier 7-thia-8-oxoguanosine was evaluated in mice against the hepatotropic Adames strain of Punta Toro virus. When administered intraperitoneally in divided doses, significant protection from death was conferred at doses of 50 and 100 mg/kg/day given 24 and 17 h pre-virus...

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Detalles Bibliográficos
Autores principales: Smee, Donald F., Huffman, John H., Gessaman, Ann C., Huggins, John W., Sidwell, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133823/
https://www.ncbi.nlm.nih.gov/pubmed/1716090
http://dx.doi.org/10.1016/0166-3542(91)90069-4