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Prophylactic and therapeutic activities of 7-thia-8-oxoguanosine against Punta Toro virus infections in mice
The biological response modifier 7-thia-8-oxoguanosine was evaluated in mice against the hepatotropic Adames strain of Punta Toro virus. When administered intraperitoneally in divided doses, significant protection from death was conferred at doses of 50 and 100 mg/kg/day given 24 and 17 h pre-virus...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133823/ https://www.ncbi.nlm.nih.gov/pubmed/1716090 http://dx.doi.org/10.1016/0166-3542(91)90069-4 |