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Altered pathogenicity in the liver induced by a mouse hepatitis virus type 3 thermosensitive mutant
Intraperitoneal inoculation into sensitive BALB/c mice of D85, a thermosensitive (ts) mutant, provokes acute hepatitis followed by recovery of the mice. The ts mutant was able to replicate in the liver. However, the maximal viral titre was obtained 2 days later than was the case with the wild-type (...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ireland Ltd.
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133862/ https://www.ncbi.nlm.nih.gov/pubmed/1655870 http://dx.doi.org/10.1016/0168-8278(91)90865-9 |